Migraines and other debilitating headaches can completely interrupt your life with excruciating pain, nausea, vomiting and sensitivity to light and sounds. Let Kate Nicole Wellness Center help you get back on track quickly and avoid long waits in busy ER or urgent care clinics. 

IV Vitamin infusions for migraines. Everything you need to know

Our IV starts with 1 liter of normal saline to which we add selected B vitamins shown in scientific literature to help drive methylation and oxidative phosphorylation which can be disrupted with migraines. A recent 2015 review article (1) of the use of vitamins in migraines points to the effective use of B2 (riboflavin), B12 (cobalamin) and B6 (pyroxidine) as having powerful therapeutic effects in migraines.  One of the therapeutic interventions of urgent emergency room treatment for migraines is aggressive hydration. This, in itself, can be therapeutic and help minimize your headache.

Two different high-strength anti-nausea medications can also be added to this IV under the right circumstances. In a 2012 review of Emergency Room treatment of migraines in pediatric and adult populations, the use of dopamine antagonists such a metoclopramide showed good results. In addition, Zofran, Toradol and hydration are established and safe migraine symptom treatments. All of which can be included in this IV after a review of your medical history.

In some cases we also add Toradol—a high-strength, long-acting non-narcotic, non-steroidal anti-inflammatory (NSAID) to combat pain. Magnesium sulfate also reduces inflammation, relaxes muscles and blood vessels as well as modulates calcium ion channels within our cells which trigger the release of neurotransmitters. Migraine patients were found to be more likely than non-Migraineurs to be magnesium deficient when their blood is tested.  One thing that is important to realize is that labs which check only our blood levels may appear normal (in the presence of a deficiency in our central nervous system) because magnesium levels are difficult to maintain in tissue, especially the brain.

Possible side effects of mag sulfate include:

  • Facial flushing
  • Hypotension
  • Lightheadedness
  • Diarrhea

Once  you've finished you  custom-designed 45-minute infusion we hope you will be feeling better. If you suffer from migraines you know that treatment in a quiet, dark environment is best and sleep should be encouraged.

Note: The addition of Toradol and anti-nausea medicine will be decided only after careful review of your medical history and are included in the price.


  1. Shaik MM, Gan SH. Vitamin Supplementation as Possible Prophylactic Treatment against Migraine with Aura and Menstrual Migraine. BioMed research international2015.
  2. Gelfand AA, Goadsby PJ. Treatment of pediatric migraine in the emergency room. Pediatric neurology, 47(4), 233-241.